|Awarded On||August 18, 2021|
|Title||Recruitment of First-Time, Tenure-Track Faculty Members|
|Award Mechanism||Recruitment of First-Time, Tenure-Track Faculty Members|
|Institution/Organization||The University of Texas Southwestern Medical Center|
|Principal Investigator/Program Director||Seungwon Choi|
|Cancer Sites||All Sites|
|Summary of Goals and Objectives||
Many cancer patients experience severe chronic pain, which in turn can lead to chronic stress in cancer patients, promoting tumor development and creating a vicious cycle. Therefore, effective pain management is a key to not only improving cancer patients’ quality of life but also slowing down the progression of cancer. Spinal cord projection neurons are attractive therapeutic targets for treating cancer pain because they carry all pain signals emanating from the tumor microenvironment to the brain. In my postdoctoral research, I identified two genetically defined populations of spinal projection neurons (Tac...