|Grant ID: RR190034|
Recruitment of First-Time, Tenure-Track Faculty Members
Dana-Farber Cancer Institute and Harvard Medical School
May 15, 2019
Glioma is the most common form of brain cancer and affects cells that support brain function. Gliomas account for a quarter of childhood cancers, arise throughout adulthood, can be deadly.
A cancer biologist at the University of Texas Southwestern Medical Center is studying gliomas through the lens of their altered metabolism, with an eye toward developing novel therapeutics designed to target cancer cells without harming normal ones.
Samuel McBrayer was recruited in 2019 to the Children’s Medical Center Research Institute at UT Southwestern, from the Dana-Farber Cancer Institute and Harvard Medical School, where he was a postdoctoral fellow. He received a First-Time Tenure-Track Award from CPRIT.
Some gliomas are among cancers that arise from mutations in genes that affect cell metabolism, or how cells utilize resources. In particular, gliomas have mutations in the pathways that cells use to oxidize and release stored energy from proteins, fats, and carbohydrates.