Daehwan Kim, Ph.D.
The University of Texas Southwestern Medical Center
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|Grant ID: RR170068|
Recruitment of First-Time, Tenure-Track Faculty Members
Johns Hopkins University, School of Medicine
August 16, 2017
The entire human genome consists of six billion letters; if it had to be stored in books it would fill a library with thousands of volumes. This poses a challenge for scientists and physicians who are looking for single-letter typos — corresponding to genetic defects or cancer — in this multi-volume encyclopedia. Especially since normal genomes, coding for characteristics such as eye or hair color, can vary between individuals.
Now a computational biologist at The University of Texas Southwestern Medical Center proposes to find a new way to quickly compare genetic sequences with the entire reference volume — a task that currently requires either using incomplete sequences or enormous computing power.