Yun Huang, PhD

  • Recruited to: Texas A&M University System Health Science Center
  • Recruited from: La Jolla Institute for Allergy and Immunology in California
  • Award: First-Time, Tenure-Track Faculty Member

Dr. Yun Huang received her doctorate in biochemistry from Georgia State University, where she worked to develop biosensors for real-time calcium sensing and dissection of the structure-function relations of the calcium-sensing receptor. In 2009, she joined Dr. Anjana Rao’s laboratory at the Immune Disease Institute at Harvard Medical School as a GSK-Immune Disease Institute Alliance Fellow and Leukemia and Lymphoma Society Fellow.

Recognized for her research on epigenetics (factors that alter gene expression without changing genetic code), Dr. Huang has significantly contributed to the functional characterization of the ten eleven translocation (TET) enzymes. In fact, her research linked these enzymes to essential biological processes, as well as to cancerogenesis. Ultimately, her work allowed other researchers to improve their understanding of the different processes cancer cells use to reprogram their epigenome.

At the Center for Epigenetics and Disease Prevention at the Texas A&M University Health Science Center’s Institute of Biosciences & Technology (IBT) in Houston, Dr. Huang is conducting research on how mutations in TET enzymes allow cancer cells to reshape their epigenome to grow, metastasize, and evade the body’s own natural defenses.